Clinical Edge

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Hysteroscopic Polypectomy and Start of IVF

Does time interval affect outcomes?

Waiting 2 or more menstrual cycles after hysteroscopic polypectomy to undergo ovarian stimulation did not necessarily yield superior outcomes, thus patients can undergo ovarian stimulation after their next menses without affecting IVF-ET outcomes, according to a study of 487 patients. Patients were divided into 3 groups based on the time interval between hysteroscopic polypectomy and the start of a fresh IVF-ET cycle (group 1 underwent IVF-ET after their next menses, group 2 after 2 or 3 menstrual cycles, and group 3 after more than 3 menstrual cycles.). Researchers found:

• Ovarian stimulation outcomes were similar among groups.

• There were no differences in the mean number of embryos transferred.

• Overall pregnancy outcomes were similar for groups 1, 2, and 3.

Citation: Pereira N, Amrane S, Estes JL, et al. Does the time interval between hysteroscopic polypectomy and start of in vitro fertilization affect outcomes? [Published online ahead of print November 19, 2015]. Fertil Steril doi: 10.1016/j.fertnstert.2015.10.028.