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Racial Disparities in Patients with Uterine Serous Carcinoma

Gynecol Oncol; ePub 2016 Aug 26; Mahdi, Han, et al

While survival outcomes of both white and African American patients with uterine serous carcinoma (USC) improved over 3 time periods, African American patients continued to have worse outcomes compared to white patients, a recent study found. Women with USC were identified using the SEER database from 1988 to 2011 (n=7,667) and divided into 3 time periods: 1988-1997, 1998-2004, and 2005-2011. Overall (OS) and disease-specific survivals (DSS) were estimated. Researchers found:

• African American patients were younger and less likely to have cancer directed surgery and extensive lymphadenectomy when compared to white patients over the 3 time periods.

• African American race was significantly associated with worse DSS and OS in the 3 time periods compared to white race.

• African American patients were 29% in 1988 and 34% in 2005-2011 more likely to die from uterine cancer compared to whites; a slight improvement over time was observed.

• African American patients were 46% in 1988-1997, 39% in 1998-2004, and 26% in 2005-2011 more likely to die from any cause compared to their white counterparts.

Citation: Mahdi H, Han X, Abdul-Karim F, Vargas R. Racial disparity in survival of patients with uterine serous carcinoma: Changes in clinical characteristics, patterns of care and outcomes over time from 1988 to 2011. [Published online ahead of print August 26, 2016]. Gynecol Oncol. doi:10.1016/j.ygyno.2016.03.002.