A significant increase in intracavitary brachytherapy (ICBT) use and decrease in whole pelvic radiotherapy (WPRT) was observed among women with early-stage endometrial cancer, a recent study found. The Surveillance, Epidemiology, and End Results Program was used to identify surgically treated stage I-II endometrial cancer between 1983 and 2012 (type 1, n=79,474; type 2, n=25,020). Researchers found:
- ICBT use exceeded WPRT use in 2003 for type 1 stage IA, and in 2007 for type 1 stage IB and type 2 stage IA diseases.
- The number of sampled pelvic nodes significantly increased over time in type 1-2 stage I-II diseases.
- On multivariable analysis, the extent of sampled pelvic nodes was significantly associated with ICBT use for type 1 cancer.
The authors concluded that the results suggest that surgeons and radiation oncologists are evaluating the extent of pelvic lymphadenectomy when counseling women with early-stage endometrial cancer for adjuvant radiotherapy.
Matsuo K, Machida H, Ragab OM, Takiuchi T, Pham HQ, Roman LD. Extent of pelvic lymphadenectomy and use of adjuvant vaginal brachytherapy for early-stage endometrial cancer. [Published online ahead of print December 22, 2016]. Gynecol Oncol. doi:10.1016/j.ygyno.2016.12.012.
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Maternal Factors in Cervical Cancer Prevention, Womens Health Issues; ePub 2019 Jan 10; Charlton, et al
Combined Gynecologic Ca & Pelvic Floor Dysfunction Surgery, Female Pelvic Med Reconstr Surg; ePub 2018 Oct 22; McConnell, et al