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IMRT Usage in Management of Postop Uterine Cancer

Gynecol Oncol; ePub 2016 Nov 22; Osborn, et al

The use of intensity modulated radiation therapy (IMRT) for postoperative management of uterine cancer has increased significantly between 2004 and 2012, although not resulting in significantly improved survival, a recent study found. The National Cancer Database was queried and identified 7,839 women with endometrial adenocarcinoma who underwent hysterectomy followed by external beam radiation during the study period. Researchers found:

  • IMRT utilization increased from 1.9% in 2004 to 32.4% in 2012 (aOR, 24.90).
  • Black race was associated with lower IMRT usage compared to whites (OR, 0.60).
  • IMRT was not associated with significantly increased survival (HR, 0.86).
  • Black race and positive nodes were associated with decreased survival; whereas private insurance and higher income were associated with improved survival.


Osborn V, Schwartz D, Lee YC, et al. Patterns of care of IMRT usage in postoperative management of uterine cancer. [Published online ahead of print November 22, 2016]. Gynecol Oncol. doi:10.1016/j.ygyno.2016.11.017.