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IMRT Usage in Management of Postop Uterine Cancer

Gynecol Oncol; ePub 2016 Nov 22; Osborn, et al

The use of intensity modulated radiation therapy (IMRT) for postoperative management of uterine cancer has increased significantly between 2004 and 2012, although not resulting in significantly improved survival, a recent study found. The National Cancer Database was queried and identified 7,839 women with endometrial adenocarcinoma who underwent hysterectomy followed by external beam radiation during the study period. Researchers found:

  • IMRT utilization increased from 1.9% in 2004 to 32.4% in 2012 (aOR, 24.90).
  • Black race was associated with lower IMRT usage compared to whites (OR, 0.60).
  • IMRT was not associated with significantly increased survival (HR, 0.86).
  • Black race and positive nodes were associated with decreased survival; whereas private insurance and higher income were associated with improved survival.

Citation:

Osborn V, Schwartz D, Lee YC, et al. Patterns of care of IMRT usage in postoperative management of uterine cancer. [Published online ahead of print November 22, 2016]. Gynecol Oncol. doi:10.1016/j.ygyno.2016.11.017.