Clinical Edge

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Hysterectomy Outcomes for Benign & Malignant Indications

Obstet Gynecol; ePub 2016 Aug 5; Wallace, Fazzari, et al

There is more than a 2-fold higher complication rate with hysterectomies performed for gynecologic malignancies when compared with those performed for benign indications, according to a recent study. The study included 59,525 eligible women who underwent hysterectomy in the US for either benign (n=49,331) or malignant (n=10,194) indications from January 2008 to December 2012. Researchers found:

  • All complications, including wound complications, venous thromboembolism, urinary tract infection, sepsis, blood transfusion, death, unplanned readmission, and returns to the operating room, were significantly more common for malignant hysterectomies.
  • Overall rate of complications for benign cases was 7.9% vs 19.4% for malignant hysterectomy.
  • Median operating time for laparoscopy in benign cases was significantly longer than for open or vaginal hysterectomy procedures.
  • Median operating time in malignant cases was significantly longer than for benign cases.


Wallace SK, Fazzari MJ, Chen H, Cliby WA, Chalas E. Outcomes and postoperative complications after hysterectomies performed for benign compared with malignant indications. [Published online ahead of print August 5, 2016]. Obstet Gynecol. doi:10.1097/AOG.0000000000001591.