Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Hypothyroidism and Reproductive Goals

Meeting goals after cancer treatment

Women who reported hypothyroidism after cancer treatment were twice as likely to fail to achieve their desired family size, according to a study of 1,282 cancer survivors. After adjusting for age and other potential confounders, the study found that women reporting hypothyroidism after cancer treatment were:

• Twice as likely to fail to achieve desired family size (adjusted OR 1.91) and be childless (adjusted OR 2.13).

• More likely to report having unprotected intercourse for at least 6 months without conceiving (adjusted OR 1.37).

• More likely to be counseled on the risks for impaired fertility or a shortened reproductive window.

Citation: Chin HB, Jacobson MH, Interrante JD, Mertens AC, Spencer JB, Howards PP. Hypothyroidism after cancer and the ability to meet reproductive goals among a cohort of young adult female cancer survivors. [Published online ahead of print October 13, 2015]. Fertil Steril. doi: 10.1016/j.fertnstert.2015.09.031.