The rarity of human papillomavirus (HPV) in the oral cavity and fingernails suggested that oral/fingernail HPV did not account for a significant fraction of HPV in genital sites in mid-adult women, according to a study of 409 women aged 30 to 50 years who were followed up for 6 months. Researchers found:
• Prevalence of detecting HPV in the oral cavity (2.4%) and fingernails (3.8%) was low compared with the vagina (33.1%).
• Concordance across anatomical sites was poor.
• Concurrent vaginal infections with the same HPV type (OR=101.0) and vaginal HPV viral load were each associated with fingernail HPV detection.
• Abnormal Papanicolaou history (OR=11.1), lifetime number of male vaginal sex partners at least 10, and lifetime number of open-mouth kissing partners at least 16, were each associated with oral HPV detection.
Citation: Fu TC, Hughes JP, Feng Q, et al. Epidemiology of human papillomavirus detected in the oral cavity and fingernails of mid-adult women. [Published online ahead of print October 30, 2015]. Sex Transm Dis. doi: 10.1097/OLQ.0000000000000362.
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