Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Guideline Care and Survival in Women with Ovarian Ca

Gynecol Oncol; ePub 2017 Mar 31; Warren, et al

Guideline care improves survival for women with ovarian cancer, yet guideline care is underutilized, a recent study found. Receipt of guideline care and 2-year cause-specific survival was assessed in this retrospective cohort analysis that included 6,427 women diagnosed with ovarian cancer in 2002 and 2011. Researchers found:

  • Receipt of guideline care improved modestly from 2002 to 2011.
  • However, less than half of women received guideline surgery with no increase from 2002 to 2011.
  • Multiagent chemotherapy use increased, but rates remained low.
  • Most women consulted a gynecologist oncologist in 2011 yet did not receive guideline care.
  • Low rates of guideline care may explain lack of improvement in 2-year survival rates.


Warren JL, Harlan LC, Trimble EL, Stevens J, Grimes M, Cronin KA. Trends in the receipt of guideline care and survival for women with ovarian cancer: A population-based study. [Published online ahead of print March 31, 2017]. Gynecol Oncol. doi:10.1016/j.ygyno.2017.03.016.