Fertility-sparing surgery was not associated with increased risk of death in young women with stage I epithelial ovarian cancer when compared with conventional surgery, a new study found. The cohort study identified women aged <40 years diagnosed with stage IA and unilateral IC epithelial ovarian cancer between 2004 and 2012. Primary outcome was time from diagnosis to death. Researchers found:
- 1,726 women were included; 825 (47.8%) underwent fertility-sparing surgery.
- 30 deaths were observed among women who underwent fertility-sparing surgery and 37 deaths among propensity-matched women who underwent conventional surgery after a median follow-up of 63 months.
- Fertility-sparing surgery was not associated with hazard of death (HR 0.80).
- The probability of survival 10 years after diagnosis was 88.5% in the fertility-sparing group and 88.9% in the conventional surgery group.
Melamed A, Rizzo AE, Nitecki R, et al. All-cause mortality after fertility-sparing surgery for stage I epithelial ovarian cancer. [Published online ahead of print June 6, 2017]. Obstet Gynecol. doi:10.1097/AOG.0000000000002102.