Higher levels of wine consumption were generally associated with ovarian cancer risk reductions, and these reductions may be stronger for red wine, according to a study of 1,144 invasive epithelial ovarian cancer cases and 2,513 controls in a population-based, case-control study. The study investigated adult lifetime and type (beer, wine, spirits) of consumption and risk and determined:
• Wine consumption was associated with a risk reduction (aOR=0.67) relative to non-drinkers, but not beer (aOR=1.06), or spirits (aOR=0.98).
• The reduced risk was stronger for exclusive red wine drinkers (aOR=0.44) than white wine drinkers (aOR=0.79).
• Wine consumption initiated prior to age 50 was associated with a risk reduction, but not drinking initiated after 50 years of age.
• Guideline concordant alcohol consumption does not increase ovarian cancer risk.
Citation: Cook LS, Leung ACY, Swenerton K, et al. Adult lifetime alcohol consumption and invasive epithelial ovarian cancer risk in a population-based care-control study. [Published online ahead of print December 12, 2015]. Gynecol Oncol. doi: 10.1016/j.ygyno.2015.12.005.
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