Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Systematic Review Indicates Cutaneous Laser Therapy May Be Safe During Pregnancy

Key clinical point: Low-level evidence indicates that cutaneous laser therapy is safe during pregnancy.

Major finding: Among 380 treated patients, the only clinically significant treatment-emergent adverse event was premature rupture of the membranes occurring 4 days after the patient received CO2 laser therapy. She had a normal delivery approximately 1 week later.

Study details: A systematic review of 22 studies published from 1994 to 2015.

Disclosures: The reviewers reported no funding sources or conflicts of interest.


Wilkerson EJ et al. Dermatol Surg. 2019 Jun;45(6):818-28.