Contraceptive efficacy or continuation did not differ significantly in head-to-head trials comparing contraceptive use among 1,503 women aged 25 years or younger. Five trials were included in the criteria and the study compared the following contraceptives: combined oral contraceptive (COC) vs. transdermal contraceptive patch, vaginal contraceptive ring, or levonorgestrel intrauterine system 20 µg/day (LNG-IUS 20); LNG-IUS 12 µg/day (LNG-IUS 12) vs. LNG-IUS 16 µg/day (LNG-IUS 16); and LNG-IUS 20 vs. the copper T380A intrauterine device (IUD). Researchers found:
• The COC group had a higher proportion of women who discontinued for “other personal reasons” compared with the group assigned to the LNG-IUS 20.
• Trial comparing LNG-IUS 12 vs. LNG-IUS 16 showed similar efficacy over 1 and 3 years.
• Continuation was at least 75% at 6 to 36 months in 3 trials that examined different LNG-IUS.
Citation: Krashin J, Tang JH, Mody S. Lopez LM. Hormonal and intrauterine methods for contraception for women aged 25 years and younger. Cochrane Database Syst Rev. [Published online ahead of print August 17, 2015]. doi: 10.1002/14651858.CD009805.pub3.
This Week's Must Reads
Must Reads in Contraception
Bleeding and Spotting with the LNG 13.5 mg IUS, Contraception; ePub 2019 Mar 1; Shimoni, et al
Contraception and Chronic Opioid Prescriptions, Contraception; ePub 2019 Feb 11; Ray-Griffith, et al
Hormonal Contraception & Coexisting Medical Conditions, Obstet Gynecol; ePub 2019 Feb; Allen, et al
Contraceptive Switching & Discontinuation, Am J Obstet Gynecol; ePub 2018 Dec 18; Simmons, et al
Efficacy of a Levonorgestrel 52-mg IU System, Obstet Gynecol; ePub 2018 Dec 4; Teal, et al