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Update on Immunization and Pregnancy

Obstet Gynecol; 2017 Sep; ACOG Comm on Obstet Pract

The American College of Obstetricians and Gynecologists (ACOG) has issued a committee opinion that offers an update on immunization and pregnancy for tetanus, diphtheria, and pertussis vaccination. The update included the following ACOG recommendations:

  • Obstetric care providers should administer the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine to all pregnant patients during each pregnancy, as early in the 27–36-weeks-of-gestation window as possible.
  • Pregnant women should be counseled that the administration of the Tdap vaccine during each pregnancy is safe and important to make sure that each newborn receives the highest possible protection against pertussis at birth.
  • Obstetrician–gynecologists are encouraged to stock and administer the Tdap vaccine in their offices.
  • Partners, family members, and infant caregivers should be offered the Tdap vaccine if they have not previously been vaccinated.
  • If not administered during pregnancy, the Tdap vaccine should be given immediately postpartum if the woman has never received a prior dose of Tdap as an adolescent, adult, or during a previous pregnancy.
  • There are certain circumstances in which it is appropriate to administer the Tdap vaccine outside of the 27–36-weeks-of-gestation window.
  • If a pregnant woman is vaccinated early in her pregnancy, she does not need to be vaccinated again during 27–36 weeks of gestation.


Update on immunization and pregnancy: tetanus, diphtheria, and pertussis vaccination. Committee Opinion No. 718. American College of Obstetricians and Gynecologists. Obstet Gynecol. 2017;130:e153–7.