Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Benefits and Safety of HPV Vaccination

Obstet Gynecol; ePub 2017 Mar 24; O’Neil Eckert, et al

The American College of Obstetricians and Gynecologists (ACOG) Committee of Adolescent Health Care has issued a committee opinion on human papillomavirus (HPV) vaccination, including the benefits and safety of HPV vaccination and the vital role OB/GYNs can play in its administration. Among the recommendations and conclusions:

  • It is crucial that OB/GYNs and other health care providers educate parents and patients on the benefits and safety of HPV vaccination and offer HPV vaccines in their offices.
  • OB/GYNs play a critical role in women’s care and should assess and vaccinate adolescent girls and young women with HPV vaccine during the catch-up period (ages 13–26 years).
  • OB/GYNs can use well-women visits as an opportunity to provide counseling to parents and encourage them to speak to their children’s health care providers to request HPV vaccination at the targeted age range of 11–12 years.
  • The CDC and the College recommend routine HPV vaccination for females and males aged 9–26 years.
  • Although HPV vaccination in pregnancy is not recommended, neither is routine pregnancy testing before vaccination. If the HPV vaccine series was interrupted for pregnancy, the series should be resumed postpartum with the next dose.
  • HPV vaccines can and should be given to breastfeeding women 26 years and younger who have not previously been vaccinated.


Human papillomavirus vaccination. Committee opinion No. 641. American College of Obstetricians and Gynecologists. [Published online ahead of print March 24, 2017]. Obstet Gynecol. doi:10.1097/AOG.0000000000002052.