While breast cancer hormone-receptor subtype is a strong and consistent predictor of breast cancer outcomes, significant and independent influences of area-level socio-economic status and healthcare access may also be critical in eliminating breast cancer outcome disparities. This according to a study of 456,217 breast cancer patients from 2000 to 2010 that examined the influence of area-level socio-economic status and healthcare access in addition to tumor hormone-receptor subtype on individual breast cancer state, treatment, and mortality among Non-Hispanic black, Non-Hispanic white, and Hispanic US adults. Researchers found:
• The average numbers of oncology hospitals per million population in counties with Non-Hispanic black, Non-Hispanic white, and Hispanic women were 8.1, 7.7, and 5.0, respectively; and the average number of medical doctors per million were 100.7, 854.0, and 866.3, respectively.
• Non-Hispanic black women (HR=1.39) and Hispanic women (HR=1.05) had significantly higher breast cancer mortality compared to Non-Hispanic white women even after adjusting for hormone-receptor subtype, area-level socio-economic status, and area-level healthcare costs.
• Lower county-level socio-economic status and healthcare accesses measures were significantly and independently associated with stage at presentation, surgery, and radiation treatment as well as mortality after adjusting for age, race/ethnicity, and HR subtype.
Citation: Akinyemiju T, Moore JX, Ojesina AI, Waterbor JW, Altekruse SF. Racial disparities in individual breast cancer outcomes by hormone-receptor subtype, area-level socio-economic status and healthcare resources. [Published online ahead of print June 2, 2016]. Breast Cancer Res Treat. doi:10.1007/s10549-016-3840-x.