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Pretreatment Breast MRI in Women Undergoing BCT

Cancer; ePub 2016 Dec 16; Vapiwala, et al

In women undergoing breast conservation therapy (BCT), breast magnetic imaging (MRI) during the initial evaluation had no significant impact on 15-year rates for local control, overall survival, freedom from distant metastases, or contralateral breast cancer, a recent study found. This study included 755 women with ductal carcinoma in situ or early-stage invasive breast cancer that underwent breast-conserving surgery, followed by definitive breast radiotherapy between 1992 and 2001. Researchers found:

  • There were 49 local failures (15 women with and 34 women without breast MRI, respectively) at median follow-up of 13.8 years.
  • No differences were observed between women with and without breast MRI with regard to 15-year rates of overall survival (77% vs 71%), freedom from distant metastases (86% vs 90%), and contralateral breast cancer (10% vs 8%).
  • There was no significant impact of breast MRI on local failure.

Citation:

Vapiwala N, Hwang WT, Kushner CJ, Schnall MD, Freedman GM, Solin LJ. No impact of breast magnetic resonance imaging on 15-year outcomes in patients with ductal carcinoma in situ or early-stage invasive breast cancer managed with breast conservation therapy. [Published online ahead of print December 16, 2016]. Cancer. doi:10.1002/cncr.30479.