Clinical Edge

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Pretreatment Breast MRI in Women Undergoing BCT

Cancer; ePub 2016 Dec 16; Vapiwala, et al

In women undergoing breast conservation therapy (BCT), breast magnetic imaging (MRI) during the initial evaluation had no significant impact on 15-year rates for local control, overall survival, freedom from distant metastases, or contralateral breast cancer, a recent study found. This study included 755 women with ductal carcinoma in situ or early-stage invasive breast cancer that underwent breast-conserving surgery, followed by definitive breast radiotherapy between 1992 and 2001. Researchers found:

  • There were 49 local failures (15 women with and 34 women without breast MRI, respectively) at median follow-up of 13.8 years.
  • No differences were observed between women with and without breast MRI with regard to 15-year rates of overall survival (77% vs 71%), freedom from distant metastases (86% vs 90%), and contralateral breast cancer (10% vs 8%).
  • There was no significant impact of breast MRI on local failure.


Vapiwala N, Hwang WT, Kushner CJ, Schnall MD, Freedman GM, Solin LJ. No impact of breast magnetic resonance imaging on 15-year outcomes in patients with ductal carcinoma in situ or early-stage invasive breast cancer managed with breast conservation therapy. [Published online ahead of print December 16, 2016]. Cancer. doi:10.1002/cncr.30479.