Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Beyond baseline, DBT no better than mammography for dense breasts

Key clinical point: In women with extremely dense breasts, digital breast tomosynthesis (DBT) does not outperform digital mammography (DM) after the initial exam.

Major finding: For baseline screening in women aged 50-59 years, recall rates per 1,000 exams dropped from 241 with DM to 204 with DBT. Cancer detection rates per 1,000 exams in this age group increased from 5.9 with DM to 8.8 with DBT. On follow-up exams, recall and cancer detection rates varied by patients’ age and breast density.

Study details: Review of 1,584,079 screenings in women aged 40-79 years.

Disclosures: The research was funded by the National Cancer Institute and the Patient-Centered Outcomes Research Institute through the Breast Cancer Surveillance Consortium. The study lead reported grants from GE Healthcare.


Lowry K et al. JAMA Netw Open. 2020 Jul 1;3(7):e2011792.