Drs. Hashim and Goldenberg and Mr. Levy are from the Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York. Dr. Cohen is from AboutSkin Dermatology and DermSurgery, Greenwood Village, Colorado; the Department of Dermatology, University of Colorado Denver, Aurora; and the Department of Dermatology, University of California, Irvine.
Drs. Hashim and Goldenberg and Mr. Levy report no conflict of interest. Dr. Cohen is an advisory board member, clinical researcher, and consultant for Allergan, Inc, and Galderma Laboratories, LP; a consultant and speaker for Sciton, Inc; and a clinical researcher for CROMA-PHARMA GmbH and Suneva Medical, Inc.
Correspondence: Gary Goldenberg, MD, Department of Dermatology, Icahn School of Medicine at Mount Sinai, 5 E 98th St, New York, NY 10029 (email@example.com).
Microneedling therapy continues to evolve with a range of applications now emerging in dermatology. As PRP has gained popularity, there has been increased interest in its utilization to amplify the regenerative effects of microneedling. Although the number of direct comparisons examining microneedling with and without PRP is limited, the available evidence indicates that the addition of PRP may improve cosmetic outcomes. These results have been demonstrated primarily in the management of acne scars, but favorable effects may extend to other indications. Continued study is warranted to further quantify the degree of these benefits and to elucidate optimal treatment schedules.
In addition, it is important to consider a cost-benefit analysis of PRP. The price of PRP varies depending on the clinical site but in certain cases may double the cost of a microneedling treatment session. Although studies have demonstrated a statistically significant benefit to PRP, the clinical significance of this supplementary treatment must be weighed against the increased expense. A discussion should take place with the consideration that microneedling alone can provide a satisfactory result for some patients.