African-American race was not independently associated with a higher rate of cerebral microbleed (CMB) burden when compared to Caucasians after adjusting for potential confounders, according to a recent study. In addition, researchers did not observe a significant racial difference regarding the location and prevalence of multiple CMBs (CMBs ≥ 5). Using natural language processing, they extracted all brain MRIs performed during a 2-year period (2012-2013) when the report indicated the presence of CMB. All the extracted MRI studies were evaluated for number and location of CMBs, prior stroke, and deep white matter lesion.
A total 167 patients (mean age, 63 ± 15 years, 49% men, 77% African-American, median CMB count: 8) with ≥1 CMBs on their brain MRI were included in this study. They found:
- There was no significant difference between the 2 groups in terms of CMB locations, but there was a significant difference between African-American and Caucasian patients in terms of number of CMBs (16.5 ± 18 vs 6.5 ± 5.5).
- The prevalence of multiple CMBs (CMBs ≥ 5) was similar among African-Americans and Caucasians (72% vs 55%).
Noorbakhsh-Sabet N, Tsivgoulis G, Shahjouel S, et al. Racial difference in cerebral microbleed burden among a patient population in the mid-South United States. [Published online ahead of print June 23, 2018]. J Stroke Cerebrovasc Dis. doi:10.1016/j.jstrokecerebrovasdis.2018.05.031.
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