Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Demographic Characteristics in Persons with MS

J Int Neuropsychol Soc; 2018 Feb; Costa, et al

When comparing differences in functioning between multiple sclerosis (MS) disease courses, attention should be paid to the demographic characteristics of the samples, according to a recent study. 21 persons with relapsing-remitting MS (RRMS group), 21 with progressive MS (PMS group), and 21 healthy participants (HCs), matched on age, education, and time post-diagnosis, completed tests of cognitive abilities, motor functions, and everyday functional activities. Researchers found:

  • The 2 groups with MS did not differ on cognitive performance.
  • Poorer performance in processing speed was noted in both MS groups in comparison with the HC group.
  • Motor function was worse for the PMS group compared with the HC and RRMS groups.
  • The RRMS group showed poorer upper limb functioning compared to the HC group.
  • The PMS group had more difficulty with everyday activities as compared with both the RRMS and HC group.

Costa SL, DeLuca J, Sandroff BM, Goverover Y, Chiaravalloti ND. Role of demographic and clinical factors in cognitive functioning of persons with relapsing-remitting and progressive multiple sclerosis. J Int Neuropsychol Soc. 2018;24(2):139-146. doi:10.1017/S1355617717000777.

This Week's Must Reads

Coexisting Dementia Rising Among Stroke Patients, J Stroke Cerebrovasc Dis; ePub 2018 Mar 14; Sherzai, et al

Excessive Daytime Sleepiness and β-Amyloid Buildup, JAMA Neurology; ePub 2018 Mar 12; Carvalho, et al

Cognitive Impairment and ICAS in General Population, Neurology; ePub 2018 Mar 9; Suri, Zhou, et al

FDA Approves Apadaz for Acute Pain Relief, KemPharm, Inc. news release; 2018 Feb 23

Must Reads in Multiple Sclerosis

Sun Exposure Associated with Lower MS Risk, Neurology; ePub 2018 Mar 7; Tremlett, et al

BEEMS Improved Several Outcomes in Patients with MS, Neurology; ePub 2018 Feb 27; Hebert, Corboy, et al

Factors Linked with Early Initiation of DMD Treatment, Curr Med Res Opin; ePub 2018 Mar 1; Edwards, et al

Predicting Episodic Memory Loss in Patients with MS, Mult Scler; ePub 2018 Mar 7; Koenig, et al

Diet Characteristics Examined in People with MS, Mult Scler Relat Disord; ePub Feb 27; Fitzgerald, et al