Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Demographic Characteristics in Persons with MS

J Int Neuropsychol Soc; 2018 Feb; Costa, et al

When comparing differences in functioning between multiple sclerosis (MS) disease courses, attention should be paid to the demographic characteristics of the samples, according to a recent study. 21 persons with relapsing-remitting MS (RRMS group), 21 with progressive MS (PMS group), and 21 healthy participants (HCs), matched on age, education, and time post-diagnosis, completed tests of cognitive abilities, motor functions, and everyday functional activities. Researchers found:

  • The 2 groups with MS did not differ on cognitive performance.
  • Poorer performance in processing speed was noted in both MS groups in comparison with the HC group.
  • Motor function was worse for the PMS group compared with the HC and RRMS groups.
  • The RRMS group showed poorer upper limb functioning compared to the HC group.
  • The PMS group had more difficulty with everyday activities as compared with both the RRMS and HC group.

Costa SL, DeLuca J, Sandroff BM, Goverover Y, Chiaravalloti ND. Role of demographic and clinical factors in cognitive functioning of persons with relapsing-remitting and progressive multiple sclerosis. J Int Neuropsychol Soc. 2018;24(2):139-146. doi:10.1017/S1355617717000777.

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Treatment Outcomes Post-Surgery for Moyamoya Disease, J Neurol; ePub 2018 Sep 8; Kahn, Kaur, Stein, et al

Must Reads in Multiple Sclerosis

Pediatric Onset MS Linked with Reduced Parental QOL, Mult Scler; ePub 2018 Aug 30; O’Mahony, et al

Depressive Symptoms Negatively Impact on MS, J Neuropsychiatry Clin Neurosci; ePub 2018 Sep 6; Gill, et al

Evaluation of the MULES Picture Naming Test, J Neurol Sci; ePub 2018 Aug 23; Seay, Akhand, et al

Postrelapse Rehabilitation Use in MS Examined , Int J MS Care; ePub 2018 Sep 5; Asano, Eitzen, et al

Thalamic White Matter in Patients with MS, Hum Brain Mapp; 2018 Oct; Bergsland, et al