Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Demographic Characteristics in Persons with MS

J Int Neuropsychol Soc; 2018 Feb; Costa, et al

When comparing differences in functioning between multiple sclerosis (MS) disease courses, attention should be paid to the demographic characteristics of the samples, according to a recent study. 21 persons with relapsing-remitting MS (RRMS group), 21 with progressive MS (PMS group), and 21 healthy participants (HCs), matched on age, education, and time post-diagnosis, completed tests of cognitive abilities, motor functions, and everyday functional activities. Researchers found:

  • The 2 groups with MS did not differ on cognitive performance.
  • Poorer performance in processing speed was noted in both MS groups in comparison with the HC group.
  • Motor function was worse for the PMS group compared with the HC and RRMS groups.
  • The RRMS group showed poorer upper limb functioning compared to the HC group.
  • The PMS group had more difficulty with everyday activities as compared with both the RRMS and HC group.
Citation:

Costa SL, DeLuca J, Sandroff BM, Goverover Y, Chiaravalloti ND. Role of demographic and clinical factors in cognitive functioning of persons with relapsing-remitting and progressive multiple sclerosis. J Int Neuropsychol Soc. 2018;24(2):139-146. doi:10.1017/S1355617717000777.

This Week's Must Reads

Social Cognitive Theory and Physical Activity in MS, Int J MS Care; 2018 May/June; Uszynski, Casey, et al

Wheeled Mobility Device Intervention Found Feasible, Int J MS Care; 2018 May/June; Rice, Isaacs, et al

Somatic Symptoms of Depression/Anxiety in MS, Int J MS Care; 2018 May/June; Jones, Salem, et al

Turning: Important Marker of Gait and Balance in MS, PLoS One; ePub 2018 Jun 7; Adusumilli, Lancia, et al

Autonomic Dysfunction Compared in Patients with MS, Clin Neurophysiol; 2018 Aug; Adamec, Crnošija, et al

Must Reads in Multiple Sclerosis

Social Cognitive Theory and Physical Activity in MS, Int J MS Care; 2018 May/June; Uszynski, Casey, et al

Wheeled Mobility Device Intervention Found Feasible, Int J MS Care; 2018 May/June; Rice, Isaacs, et al

Somatic Symptoms of Depression/Anxiety in MS, Int J MS Care; 2018 May/June; Jones, Salem, et al

Turning: Important Marker of Gait and Balance in MS, PLoS One; ePub 2018 Jun 7; Adusumilli, Lancia, et al

Autonomic Dysfunction Compared in Patients with MS, Clin Neurophysiol; 2018 Aug; Adamec, Crnošija, et al