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Admissions for Psychotic Episodes, Epilepsy Linked

Epilepsia; ePub 2018 Jul 4; Rossi, Kim, et al

An epilepsy admission was independently associated with subsequent hospital readmission for psychotic episodes, even after adjustment for confounding variables, a recent study found. There were 58,278 index admissions for epilepsy, and researchers compared this group against admissions for stroke (n=215,821) and common medical causes (pneumonia, urinary tract infection [UTI], congestive heart failure [CHF], and chronic obstructive pulmonary disease [COPD], n=973,078). Readmission rates for psychotic episodes within 90 days from discharge for index hospitalizations were calculated. They found:

  • Up to 90 days from index admission, there were 683/100,000 readmissions for psychotic episodes in the epilepsy group, 92/100,000 in the stroke group, and 58‐206/100,000 in the medical group.
  • The relative rate of readmission in the epilepsy group was highest in the first 30 days following index admission (311/100,000).
  • Unadjusted hazard ratio (HR) for readmission for psychotic episodes within 1 year in the epilepsy group compared to the stroke group was 6.58 and 4.41, compared to the medical group.
  • Confounding factors most strongly associated with psychosis readmission were documented psychosis history at the time of index admission, younger age, and lower income quartile.

Citation:

Rossi KC, Kim AM, Jetté N, Yoo JY, Hung K, Dhamoon MS. Increased risk of hospital admission for ICD‐9‐CM psychotic episodes following admission for epilepsy. [Published online ahead of print July 4, 2018]. Epilepsia. doi:10.1111/epi.14508.

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