Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Commonalities challenge the threshold of high-frequency episodic and low-frequency chronic migraine

Key clinical point: High-frequency episodic and low-frequency migraine share many characteristics.

Major finding: Approximately half of both subgroups had signs of depression.

Study details: An analysis of 16,789 patients in the Chronic Migraine Epidemiology and Outcomes Study.

Disclosures: Dr. Lipton disclosed financial relationships with Alder Biopharmaceuticals, Allergan (now AbbVie), Amgen, Biohaven, Dr. Reddy’s/Promius, Electrocore, Eli Lilly, eNeura Therapeutics, GlaxoSmithKline, Lundbeck (Alder), Merck, Pernix Therapeutics, Pfizer, Supernus, Teva, Trigemina, Axsome Therapeutics, Vector, and Vedanta. Dr. Charles disclosed he is a consultant to Amgen, Biohaven Pharmaceuticals, Eli Lilly, Lundbeck, and Novartis.


Lipton RB et al. AHS 2020, Abstract 813833.