Literature Review

Understanding Seizure Clusters in Drug-resistant Focal Epilepsy

Researchers found more clustering in patients with temporal lobe epilepsy, and they fared better after surgery if they had clustering.


In an effort to detect links between seizure clusters and as yet unknown clinical factors among patients with drug-resistant focal epilepsy, researchers performed a retrospective analysis of 764 patients. They found clustering in 23.6% of patients with temporal lobe epilepsy (TLE) and 16.9% of patients with extratemporal seizures. Unfortunately, they failed to detect any clinical factors associated with the clustering. However, they did notice that TLE patients fared better after surgery if they had a history of seizure clusters.

Asadi-Pooya AA, Nei M, Sharan A, Sperling MR. Seizure clusters in drug-resistant focal epilepsy. Epilepsia. 2016;57(9):e187-e190.

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