Literature Review

Evaluating Alternatives to Open Surgical Resection for Epilepsy

A recent review suggests clinicians should consider stereotactic electroencephalography, laser interstitial thermal therapy, and stereotactic radiosurgery



Open surgical resection is still considered the best approach for patients with epilepsy that do not respond well to medical therapy. But despite being considered the gold standard in neurosurgical care, the shortcomings of open surgical resection need to be addressed. McGovern and colleagues do so in a review published in Current Neurology and Neuroscience Reports. They point to the value of stereotactic electroencephalography, which can localize deep epileptic foci. Similarly laser interstitial thermal therapy (LITT) and stereotactic radiosurgery have advantages because they can ablate specific regions of the brain using minimally or non-invasive techniques. In the case of LITT, it can offer clinicians near real-time feedback on its effects. Neurostimulation is also worth consideration in select patients because it can reduce seizure occurrence without the need for ablation or resection

McGovern RA, Banks GP, McKhann GM 2nd. New techniques and progress in epilepsy surgery. Curr Neurol Neurosci Rep. 2016;16(7):65.

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