Literature Review

Validation of a Seizure-Detection Algorithm for Generalized Tonic-Clonic Seizures

How will this algorithm affect patient monitoring and early intervention?



In a study of 33 patients, the Brain Sentinel seizure detection algorithm detected 20 of 21 confirmed generalized tonic-clonic seizures (GTCS) using surface electromyography (sEMG) and video-EEG monitoring. One false-positive detection occurred during the postictal period following a GTCS. This is a positive step for the Brain Sentinel seizure detection algorithm, which aims to facilitate patient monitoring and early intervention. Further studies in large patient groups are needed.

Szabó CA, Morgan LC, Kantar KM, et al. Electromyography-based seizure detector: preliminary results comparing a generalized tonic-clonic seizure detection algorithm to video-EEG recordings [published online ahead of print July 20, 2015]. Epilepsia. 2015; doi:10.1111/epi.13083.

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