Literature Review

Can Nomograms Be Used to Predict Seizure Outcomes Postsurgery?

Nomograms for patients judged eligible for epilepsy surgery



Researchers at the Cleveland Clinic Epilepsy Center developed nomograms to predict freedom from seizures and Engel score of 1 (eventual freedom from seizures) based on a development cohort of 846 patients who had resective surgery between 1996 and 2011. The nomograms were tested in an external validation cohort of 604 patients from 4 epilepsy surgery centers. If these nomograms are validated they could be used to predict seizure outcomes in patients eligible for epilepsy surgery.

Jehi L, Yardi R, Chagin K, et al. Development and validation of nomograms to provide individualised predictions of seizure outcomes after epilepsy surgery: a retrospective analysis. Lancet Neurol. 2015;14(3):283-290.

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