Key clinical point: Early administration of tranexamic acid after TBI does not improve neurologic outcome at 6 months.
Major finding: Patients with TBI and ICH who received a 2-g bolus of tranexamic acid had a 50% lower rate of mortality.
Study details: A multicenter, prehospital trial that enrolled 1,063 patients with moderate to severe TBI.
REPORTING FROM AAN 2019
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Must Reads in Trauma
Psychiatric Risk Factors for Recurrent Neurotrauma, Brain Inj; ePub 2018 Jun 18; Hayward, Fessler, et al