Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Pre-existing Hypertension in Patients with Stroke

J Stroke Cerebrovasc Dis; ePub 2018 Dec 13; Valentine, et al

Patients with intracerebral hemorrhage (ICH) who have pre-existing hypertension (prHTN) have higher admission systolic blood pressure (aBP) and NIH Stroke Scale/Score (NIHSS), suggesting that prHTN may worsen reactive hypertension in the setting of ICH. This according to a recent study that sought to assess the relationship between prHTN and aBP and bleed severity. Researchers retrospectively assessed the relationship between prHTN and aBP and NIHSS in patients with ICH at 3 institutions. They found:

  • Of 251 patients, 170 (68%) had prHTN based on history of hypertension/antihypertensive use.
  • Median aBP was significantly higher in those with prHTN.
  • Patients with left ventricular hypertrophy (LVH) on electrocardiogram (ECG) or transthoracic echocardiogram (TTE) had significantly higher aBP than those without LVH.

Valentine D, Lord AS, Torres J, et al. How does preexisting hypertension affect patients with intracerebral hemorrhage? [Published online ahead of print December 13, 2018]. J Stroke Cerebrovasc Dis. doi:10.1016/j.jstrokecerebrovasdis.2018.11.023.