Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Imaging Predicts Early Postural Instability in Parkinson’s Disease

Key clinical point: Early postural instability in Parkinson’s disease is associated with gray matter pathology.

Major finding: A seven-item scale is better than the UPDRS at predicting which patients will develop early postural instability.

Study details: Study of 101 patients with newly diagnosed Parkinson’s disease and 56 healthy controls.

Disclosures: No study sponsorship was reported.


Skidmore F et al. AAN 2019, Abstract S41.004.