Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Stroke thrombolysis looks safe 31+ days after prior stroke

Key clinical point: Most risk from stroke thrombolysis following a prior stroke clusters in the first 30 days.

Major finding: Thrombolysis-induced symptomatic intracranial hemorrhage was 3.7-fold more common than in controls in the 14 days following a prior stroke.

Study details: Review of 40,396 acute ischemic stroke patients treated with thrombolysis at any of 1,522 hospitals in the Get With the Guidelines-Stroke program.

Disclosures: Dr. Shah and Dr. Xian had no disclosures. Dr. Fonarow had no relevant disclosures.


Shah S et al. Stroke. 2019 Feb;50(Suppl_1): Abstract 35.