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Treatment for Pediatric Low-Grade Glioma Associated With Poor Cognitive Outcomes

Key clinical point: Treatment for low-grade pediatric tumors entails long-term cognitive and socioeconomic decrements.

Major finding: At follow-up, mean IQ was 93.9 for surgery plus radiotherapy, 101.2 for surgery alone, and 108.5 for unaffected siblings.

Study details: An examination of 286 participants in the Childhood Cancer Survivor Study.

Disclosures: The National Cancer Institute supported the study. The authors had no disclosures.


Ris MD et al. Cancer. 2019 Jun 24. doi: 10.1002/cncr.32186.