Clinical Edge

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Tocilizumab beat azathioprine for NMOSD

Key clinical point: Relapse-free rates were higher for patients with neuromyelitis optica spectrum disorder who received tocilizumab compared with azathioprine.

Major finding: After 90 weeks of therapy, 86% of those receiving tocilizumab were relapse-free, compared with 48.1% of those on azathioprine.

Study details: Randomized, open-label head-to-head trial enrolling 118 patients with highly relapsing NMOSD.

Disclosures: The study was funded by Tianjin Medical University, Tianjin, China; Capital Medical University, Beijing; and the National Science Foundation of China. The authors reported no conflicts of interest.


Zhang C et al. ECTRIMS 2019, Abstract 140.