Higher total alcohol and red wine intake were associated with a lower cross-sectional level of neurologic disability in persons with multiple sclerosis (MS) but increased T2 hyperintense lesion volume (T2LV) accumulation, according to a recent study. MS patients (n=923) enrolled in the Comprehensive Longitudinal Investigation of Multiple Sclerosis at the Brigham and Women's Hospital (CLIMB) who completed a self-administered questionnaire about their past year drinking habits at a single time point were included in the study. Alcohol and red wine consumption were measured as servings/week. Researchers found:
- Compared to abstainers, patients drinking >4 drinks per week had a higher likelihood of a lower Expanded Disability Status Scale (EDSS) score and lower Multiple Sclerosis Severity Score (MSSS) at the time of the questionnaire.
- Similarly, patients drinking >3 glasses of red wine per week had greater odds of a lower EDSS and lower MSSS compared to nondrinkers.
- However, a faster increase in T2LV was observed in patients consuming 1–3 glasses of red wine per week compared to nondrinkers.
Diaz-Cruz C, Chua AS, Malik MT, et al. The effect of alcohol and red wine consumption on clinical and MRI outcomes in multiple sclerosis. [Published online ahead of print June 27, 2017]. Mult Scler Relat Disord. doi:10.1016/j.msard.2017.06.011.