While children with multiple sclerosis (MS) did not self-report lower health-related quality of life (HRQOL) compared to children who experienced monophasic acquired demyelinating syndrome (monoADS), the diagnosis of MS during childhood was negatively associated with parental HRQOL and family functioning. This according to a recent study that aimed to evaluate the impact of chronic disease in children ascertained as having MS and their families when compared to those with monoADS. In a national prospective cohort study of pediatric ADS, the HRQOL of children and their families was captured using the Pediatric Quality of Life Inventory (PedsQL) Modules. Researchers found:
- Participants (58 MS; 178 monoADS) provided cross-sectional HRQOL data a median (interquartile range [IQR]) of 4.1 (2.0–6.0) years after disease onset.
- The HRQOL of parents of children with MS and their family functioning was lower when compared to that of parents and families of children with monoADS; parents of children with MS reported greater emotional dysfunction, worry, worse communication, and lower family functioning irrespective of clinical disease activity.
O’Mahony J, Marrie RA, Laporte A, et al. Pediatric-onset multiple sclerosis is associated with reduced parental health–related quality of life and family functioning. [Published online ahead of print August 30, 2018]. Mult Scler. doi:10.1177/1352458518796676.