Clinical Edge

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No Link Between Overall Diet, MS Risk in Women

Mult Scler; ePub 2018 Oct 23; Rotstein, et al

There was no evidence of an association between overall diet quality and risk of developing multiple sclerosis (MS) among women, according to a recent study. >185,000 women in the Nurses’ Health Study (NHS) and Nurses’ Health Study II (NHSII) completed semi-quantitative food frequency questionnaires every 4 years. There were 480 MS incident cases. Diet quality was assessed using the Alternative Healthy Eating Index-2010 (AHEI-2010), Alternate Mediterranean Diet (aMED) index, and Dietary Approaches to Stop Hypertension (DASH) index. Researchers found:

  • None of the dietary indices, AHEI-2010, aMED, or DASH, at baseline was statistically significantly related to the risk of MS.
  • The principal component analysis identified “Western” and “prudent” dietary patterns, neither of which was associated with MS risk (HR, top vs bottom quintile: Western, 0.81 and prudent, 0.96).
  • When the analysis was repeated using cumulative average dietary pattern scores, the results were unchanged.

Citation:

Rotstein DL, Cortese M, Fung TT, Chitnis T, Ascherio A, Munger KL. Diet quality and risk of multiple sclerosis in two cohorts of US women. [Published online ahead of print October 23, 2018]. Mult Scler. doi:10.1177%2F1352458518807061.

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