Clinical Edge

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Fingolimod reduced disease activity more than glatiramer acetate in RRMS: ASSESS study results

Key clinical point: Fingolimod at a 0.5-mg dose had superior efficacy compared with glatiramer acetate in reducing disease activity in patients with relapsing-remitting multiple sclerosis.

Major finding: Annualized relapse rate was 0.153 for fingolimod 0.5 mg, versus 0.258 for glatiramer acetate (40.7% relative reduction; P = .013).

Study details: A randomized, three-armed, phase 3b study (ASSESS) enrolling 1,054 patients with relapsing-remitting multiple sclerosis.

Disclosures: Novartis sponsored the study. Dr. Cree provided disclosures related to Abbvie, Akili, Biogen, EMD Serono, GeNeuro, and Novartis.


Cree B et al. AAN 2019, Abstract 56.009.