Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Cognitive Impairment, Dysarthria in Multiple Sclerosis

Am J Speech Lang Pathol; ePub 2018 Jul 26; Feenaughty, et al

Findings from a recent study suggest the importance of employing a variety of measures to capture functional communication problems experienced by persons with multiple sclerosis (MS). 48 adults with MS and 12 healthy controls participated in this study. Cognitive testing and dysarthria diagnosis (difficult or unclear articulation of speech that is otherwise linguistically normal) determined group assignment: (a) MS with cognitive impairment (MSCI), (b) MS with a diagnosis of dysarthria and no cognitive impairment (MSDYS), (c) MS with dysarthria and cognitive impairment (MSDYS + CI), and (d) MS without dysarthria or cognitive impairment (MS). Sentence Intelligibility Test scores, scaled speech severity obtained from the “Grandfather Passage,” and Communication Participation Item Bank (CPIB) scores were analyzed. Researchers found:

  • Sentence Intelligibility Test scores approached 100% for all groups.
  • Speech severity was greater for the MSDYS + CI and MSDYS groups vs controls.
  • CPIB scores were greatest for the MSDYS + CI group and were not significantly correlated with either perceptual measure.


Feenaughty L, Tjaden K, Weinstock-Guttman B, Benedict RHB. Separate and combined influence of cognitive impairment and dysarthria on functional communication in multiple sclerosis. [Published online ahead of print July 26, 2018]. Am J Speech Lang Pathol. doi:10.1044/2018_AJSLP-17-0174.

This Week's Must Reads

Hospital Readmission After Seizure Discharge, Neurology; ePub 2018 Dec 21; Blank, et al

VP Shunts and Post-Operative Complications Assessed, J Stroke Cerebrovasc Dis; ePub 2018 Dec 20; Linzey, et al

Disparities in Inter-Hospital Helicopter Transport, J Stroke Cerebrovasc Dis; ePub 2018 Dec 11; Sarrazin, et al

Mild-to-Moderate OSA Linked with Hypertension, Sleep; ePub 2018 Dec 22; Vgontzas, et al

Aspirin Reduces Stroke Risk in Women with Prior HDP, Neurology; ePub 2018 Dec 26; Miller, Boehme, et al

Must Reads in Multiple Sclerosis

Prevalence of Asthma in Persons with MS, Mult Scler Relat Disord; ePub 2018 Dec 11; Hill, et al

Normal-Appearing White Matter in MS Examined, Neuroradiology; ePub 2018 Dec 12; Yu, et al

MS Disease Burden: Which Symptoms Matter Most?, Mult Scler Relat Disord; 2018 Oct; Barin, et al

Retinal Layer Thickness and MS Conversion Risk, Mult Scler; ePub 2018 Dec 3; Filippatou, et al

Importance of Coping and QOL in People with MS, Int J MS Care; ePub 2018 Dec 6; Grech, et al