The Montreal Cognitive Assessment (MoCA) and Mattis Dementia Rating Scale‐2 demonstrated individual strengths in screening for impairment, according to a recent study that compared their sensitivity and specificity. Both cognitive assessments were administered to training and validation cohorts. Cutoff scores were determined within the training cohort (n=85) to optimize sensitivity and specificity for cognitive impairment and were applied to an independent validation cohort (n=521). Researchers found:
- The MoCA was consistently sensitive across training and validation cohorts (90.0% and 80.3%, respectively), whereas the Mattis Dementia Rating Scale‐2 was not (87.5% and 60.3%, respectively).
- In individual domains, the MoCA remained sensitive to memory and visuospatial impairments (91.9% and 87.8%, respectively), whereas the Mattis Dementia Rating Scale‐2 was sensitive to executive impairments (86.2%).
Hendershott TR, Zhu D, Llanes S, et al. Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale‐2 in Parkinson's disease. [Published online ahead of print December 10, 2018]. Mov Disord. doi:10.1002/mds.27575.