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MRI-Guided Thalamotomy Presents New Option for ET

Mov Disord; ePub 2018 Apr 27; Fishman, et al

The overall safety profile of magnetic resonance imaging-guided focused ultrasound thalamotomy supports its role as a new option for patients with medically refractory essential tremor (ET), a recent study found. Researchers sought to determine the safety profile of magnetic resonance imaging-guided focused ultrasound unilateral thalamotomy for ET, including frequency, and severity of adverse events, including serious adverse events. 186 patients and 5 studies were included in an analysis of safety data. They found:

  • Procedure‐related serious adverse events were very infrequent (1.6%), without intracerebral hemorrhages or infections.
  • Adverse events were usually transient and were commonly rated as mild (79%) and rarely severe (1%).
  • As previously reported, abnormalities in sensation and balance were the commonest thalamotomy‐related adverse events.
Citation:

Fishman PS, Elias WJ, Ghanouni P, et al. Neurological adverse event profile of magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor. [Published online ahead of print April 27, 2018]. Mov Disord. doi:10.1002/mds.27401.