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MRI-Guided Thalamotomy Presents New Option for ET

Mov Disord; ePub 2018 Apr 27; Fishman, et al

The overall safety profile of magnetic resonance imaging-guided focused ultrasound thalamotomy supports its role as a new option for patients with medically refractory essential tremor (ET), a recent study found. Researchers sought to determine the safety profile of magnetic resonance imaging-guided focused ultrasound unilateral thalamotomy for ET, including frequency, and severity of adverse events, including serious adverse events. 186 patients and 5 studies were included in an analysis of safety data. They found:

  • Procedure‐related serious adverse events were very infrequent (1.6%), without intracerebral hemorrhages or infections.
  • Adverse events were usually transient and were commonly rated as mild (79%) and rarely severe (1%).
  • As previously reported, abnormalities in sensation and balance were the commonest thalamotomy‐related adverse events.

Fishman PS, Elias WJ, Ghanouni P, et al. Neurological adverse event profile of magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor. [Published online ahead of print April 27, 2018]. Mov Disord. doi:10.1002/mds.27401.