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CV Comorbidities Common in Veterans with PD

J Parkinson Dis; ePub 2018 Feb 17; Kotagal, et al

Cardiovascular (CV) comorbidities are common in veterans with Parkinson disease (PD) and may be more severe than in non-veteran PD populations, according to a recent study. Researchers conducted a retrospective, nested, case-control study of 29 veterans with PD and 29 non-veteran PD controls. The groups were matched for age, gender, and disease duration. Both groups underwent clinical and imaging testing as part of their participation in a larger cross-sectional PD observational study. Veterans were recruited primarily from movement disorders neurology clinics at the Ann Arbor Veterans Affairs (VA) Health System. Non-veterans were recruited primarily from analogous clinics at the University of Michigan Health System. They explored differences in CV risks factor burden between the groups and found:

  • Veterans with PD showed higher scores on the simplified Framingham 10-year general CV disease risk calculator (FR) and fewer years of self-reported education.
  • After adjusting for age, disease duration, education, and the use of antihypertensive medications, veterans showed higher FR scores and a higher intra-subject ratio of FR score to age-and-gender normalized FR score, representing an elevated component of modifiable CV risk factor burden.

Citation:

Kotagal V, Albin RL, Müller MLTM, Bohnen NI. Cardiovascular risk factor burden in veterans and non-veterans with Parkinson disease. [Published online ahead of print February 17, 2018]. J Parkinson Dis. doi:10.3233/JPD-171271.