Clinical Edge

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Migraine Comorbidity and Cognitive Performance in Focal Epilepsy

No association between migraine comorbidity and objective cognitive scores was found in a recent study involving patients with newly diagnosed focal epilepsy. The post hoc analysis included 349 participants screened for migraine with the 13 questions used in the American Migraine Prevalence and Prevention (AMPP) study. Researchers found:

  • Approximately one-fifth (21.2%) of patients with a new diagnosis of focal epilepsy screened positive for migraine.
  • There were more women and less participants employed full time among those with comorbid migraine.
  • They reported slightly more depressive and anxious symptoms than those without migraine.


Begasse de Dhaem OAJ, et al. Migraine comorbidity and cognitive performance in patients with focal epilepsy. Epilespy Behav. 2019;97:29-33. doi: 10.1016/j.yebeh.2019.05.008.