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Low vitamin D levels in patients with migraine

Key clinical point: Serum levels of 25-hydroxyvitamin D (25(OH)D) are lower in patients with migraine than healthy individuals.

Major finding: Serum levels of 25(OH)D were significantly lower in patients with migraine than control individuals (random effects model: mean difference, −4.05; 95% confidence interval, −6.34 to −1.76).

Study details: Meta-analysis of 8 studies including 8,965 participants (952 patients with migraine and 8,013 healthy controls).

Disclosures: No study sponsor was identified. The authors declared no competing interest.


Liampas I et al. Rev Neurol. 2020 Mar 30. doi: 10.1016/j.neurol.2019.12.008.