Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Comorbid Fibromyalgia in Migraine Patients

In patients with migraine, the presence of fibromyalgia (FM) is a clinical sign of a more severe migraine, a new study suggests. 102 consecutive patients with migraine aged 18-50 years were asked to complete the following self-report questionnaire for the assessment of pain-related disability, migraine-related disability, anxiety, depression, sleep disturbance, and quality of life. Researchers found:

  • 92% of patients were diagnosed with episodic migraine; 8% were diagnosed with chronic migraine (CM).
  • Comorbid FM was detected to present in 30.3% of the patients.
  • FM was more frequent in CM patients and in migraine patients with aura.
  • Headache frequency, migraine disease duration, headache impact test, MIDAS scores were significantly higher in FM (+) migraineurs.


Onder H, et al. Comorbid fibromyalgia in migraine patients: Clinical significance and impact on daily life. [Published online ahead of print June 20, 2019]. Neurol Res. doi: 10.1080/01616412.2019.1630164.