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Cognitive impairment prevalent in chronic migraine

Key clinical point: Cognitive impairment is prevalent in patients with chronic migraine (CM) even during their mildest possible headache or when headache-free.

Major finding: Patients with CM vs. those with episodic migraine had 4 times higher odds of achieving a Rey Auditory Verbal Learning Test score in the lower quartile range (odds ratio, 3.8; P = .005). In Montreal Cognitive Assessment, patients with CM demonstrated the most remarkable impairment in memory/delayed recall (65.3%), attention (46.5%), abstraction (30.6%), and language (27.1%).

Study details: The data come from a cross-sectional study of 144 patients with CM and 44 age-matched patients with low-frequency episodic migraine.

Disclosures: The authors declared no conflicts of interest.


Latysheva N et al. Arq Neuropsiquiatr. 2020 Mar 30. doi: 10.1590/0004-282X20190159.