Clinical Edge

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Burden of Syncope in Patients With Migraine

Modifiable risk factors for syncope in patients with migraine include body mass index (BMI) and tea intake, a new study found. Participants were recruited from a headache clinic and provided information of lifestyle, comorbidity, syncope, and completed the MIDAS and HADS questionnaires. Among the findings:

  • Underweight, regular tea intake, diabetes mellitus, and migraine with aura were associated with increased syncope risks.
  • Preliminary results showed that rs11172113 in LRP1 was associated with syncope risks.
  • Comorbid syncope in patients with migraine was associated with risks of depression.


Kuan AS, et al. Risk factors and psychological impact of syncope in migraine patients. [Published online ahead of print July 15, 2019]. Cephalalgia. doi: 10.1177/0333102419865253.