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Association Between Migraine and Suicidal Behavior

Headache; ePub 2017 Nov 29; Friedman, Zhong, et al

Migraineurs are at an increased risk of developing suicidal behaviors, even after controlling for comorbid depression, according to previous research. A recent study that included a national inpatient sample found that the presence of psychiatric diagnoses influences associations of suicidal behaviors with migraine. To that end, migraineurs with diagnosed comorbid psychiatric disorders may be receiving care that mitigates their risk for suicidal behaviors, since chronic conditions that do not affect the current hospitalization may not have been reported. Researchers analyzed the Nationwide Inpatient Sample of hospitalizations. Migraine, suicidal behaviors, and psychiatric disorders were identified from hospitalization discharges (2007-2012). They found:

  • 156,172,826 hospitalizations were included, of which 1.4% had a migraine diagnosis and 1.6% had a diagnosis of suicidal behavior.
  • Migraineurs had a 2.07-fold increased odds of suicidal behaviors compared with non-migraineurs.
  • Among hospitalizations with depression, migraine was associated with a 20% reduced odds of suicidal behaviors.
  • Among hospitalizations without depression, migraine was associated with 2.35-fold increased odds of suicidal behaviors.

Citation:

Friedman LE, Zhong Q-Y, Gelaye B, Williams MA, Peterlin BL. Association between migraine and suicidal behaviors: A nationwide study in the USA. [Published online ahead of print November 29, 2017]. Headache. doi:10.1111/head.13235.