Clinical Edge

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Should a Normal-Appearing Hippocampus be Resected in a Patient With Temporal Lobe Epilepsy?

Key clinical point: Sparing a normal-appearing hippocampus may be associated with a high risk of seizure recurrence.

Major finding: Among patients with surgery on the dominant side, 39.7% of patients with a spared hippocampus had a decline in verbal memory, compared with 70.4% of patients with a resected hippocampus.

Study details: A retrospective analysis of data for 152 patients who underwent surgery for temporal lobe epilepsy.

Disclosures: The study was funded by a grant from the National Institutes of Health. The investigators reported no conflicts of interest.


Morita-Sherman ME et al. AES 2019, Abstract 1.336.