Clinical Edge

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Depressive Symptoms Associated with Stroke Risk

Key clinical point: Older adults who report more depressive symptoms may be at greater risk of ischemic stroke.

Major finding: In adjusted models, participants with elevated depressive symptoms had a significantly greater risk of ischemic stroke (hazard ratio, 1.75).

Study details: An analysis of data from more than 1,100 participants in the MRI substudy of the Northern Manhattan Study.

Disclosures: The study was supported by the National Institute of Neurological Disorders and Stroke. Dr. Simonetto reported no disclosures. Coauthors disclosed personal compensation and research support from pharmaceutical and medical device companies.


Simonetto M et al. AAN 2019, Abstract S1.003.