Key clinical point: Individuals exposed to stress and trauma had a higher risk of developing neurodegenerative diseases compared with unexposed controls.
Major finding: Adults with a stress-related disorder from exposure to stress or trauma were significantly more likely than controls to develop neurodegenerative disease (hazard ratio 1.57) over approximately 5 years’ follow-up.
Study details: The data come from a population-matched and sibling cohort study including 61,748 exposed and 595,335 unexposed individuals in Sweden.
Disclosures: The researchers had no financial conflicts to disclose.
Song H et al. JAMA Neurol. 2020 Mar 9. doi: 10.1001/jamaneurol.2020.0117.