Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Nonpharmacologic interventions recommended for behavioral disturbances in dementia

Key clinical point: Among patients with dementia and behavioral disturbances, nonpharmacologic interventions – ecobiopsychosocial approaches that target the patient, caregiver, and environment—are recommended first-line measures.

Major finding: Three scenarios may warrant the consideration of pharmacologic treatment as first-line therapy: major depressive disorder with or without suicidal ideation, psychosis causing harm or potential for harm, and aggression with risk to self or others.

Study details: An overview of ways to approach the investigation and treatment of behavioral and psychotic symptoms of dementia.

Disclosures: The authors had no disclosures.


Gerlach LB et al. Clin Geriatr Med. 2020 May;36(2):315-27. doi: 10.1016/j.cger.2019.11.010.